“When bones broken, especially in the face, it is, first of all, painful, and, secondly, a person becomes defective. There is particularly difficult situation if it is oncology case. Therefore it is necessary to apply modern methods of reconstructive surgery so like that over time this part of the body can be recovered,”- Associate Professor of the Department of Theoretical and Experimental Physics of TPU Sergey Tverdokhlebov says, the head of the scientific team that develops implants.
The project is conducted by the team of scientists jointly with the Institute of Oncology. The scientists develop experimental models of implants based on the carcass of a metal grid and a biodegradable polymer composition.
“One takes the metal armature, which plans to be produced by our commercial partner – a large Moscow company “Konvent”. Further, this material integrates with the biodegradable composition - some polymers are mixed and integrated together with a titanium grid in accordance of the developed technology. The grid becomes soft enough, it can be bent, simulate and adjust to anatomical features of the skull,” - the scientist says.
This construction is fully integrated with the bone, it is able to recover part of the bone. For cancer patients it has also antirecurrent action.
“Moreover, we improve the properties of both the metal grid and the polymer. In the world there are a few groups that can modify the polymer because it is structurally much less resistant to the effects,” - Sergey Tverdokhlebov said.
The project was supported with a grant of the Federal Target Program and received funding for three years in the amount of 45 million rubles. In Russia there are no analogues of this development, while the polytechnics expect to get cheaper material than offered abroad. The medical research of the new material will be conducted by the Research Institute of Oncology.
“We proposed the idea and we will implement it in the form of “iron” and the Institute of Oncology will test this “iron” on biocompatibility, non-toxicity, cancer safety. The research will be carried out three years, further a pilot production will be opened, and together with the Moscow company “Konvent” it will be introduced,”- the scientist said.
Let us remind that the creative team under the supervision of Sergey Tverdokhlebov suggested several innovative solutions for regenerative medicine – biostents for cardiology, bioreactors for growing human tissue, unrejected implants.
In the work on the FTP project the teams of other departments and institutions of TPU are also involved: ProfessorsViktor Filimonov, Gennady Remnev, Victor Ignatov, Valery Pogrebenkov, associate professor Victor Novikov and others.